Cellular biomarkers to elucidate global warming effects on Antarctic sea urchin Sterechinus neumayeri

first_imgGlobal warming is a reality and its effects havebeen widely studied. However, the consequences for marineinvertebrates remain poorly understood. Thus, thepresent study proposed to evaluate the effect of elevatedtemperature on the innate immune system of Antarctic seaurchin Sterechinus neumayeri. Sea urchins were collectednearby Brazilian Antarctic Station ‘‘Comandante Ferraz’’and exposed to 0 (control), 2 and 4C for periods of 48 h, 2,7 and 14 days. After the experimental periods, coelomicfluid was collected in order to perform the followinganalyses: coelomocytes differential counting, phagocyticresponse, adhesion and spreading coelomocytes assay,intranuclear iron crystalloid and ultra structural analysis ofcoelomocytes. The red sphere cell was considered a biomarkerfor heat stress, as they increased in acute stress.Besides that, a significant increase in phagocytic indexeswas observed at 2C coinciding with a significant increaseof intranuclear iron crystalloid at the same temperature andsame time period. Furthermore, significant alterations incell adhesion and spreading were observed in elevatedtemperatures. The ultra structural analysis of coelomocytesshowed no significant difference across treatments. Thiswas the first time that innate immune response alterationswere observed in response to elevated temperature in a Polar echinoid.last_img read more


first_imgLEFTISTS’ HEADS EXPLODE IN RESPONSE TO KEEPING AMERICA SAFEBy Susan Stamper BrownGiven the daily liberal head explosions occurring because of President Trump’s immigration policies, one might think Trump demolished the Statue of Liberty, or worse, reintroduced school prayer, when all he did is take executive action on January 27 to protect Americans.The White House owes no apology for wanting to keep America safe. At most, the administration could consider special circumstances where the threat to the country is negligible, a step they have already committed to doing. The executive order temporarily bans immigration for those coming from jihadi-infested countries like Yemen, Sudan, Somalia, Libya, Iran and Iraq until better security screening is in place.The order also puts an indefinite ban on those coming from Syria because ISIS is extremely active there. We didn’t hear a peep from leftists when former president Obama did something similar regarding immigration from Iraq in 2011. No one should be surprised, though, given Democrats’ standards have nothing to do with safety and security and everything to do with politics and appeasement.Leftists might be thanking Trump for his actions if they weren’t so drunk with hatred for anyone or anything that even hints of American values. If they lock their doors at night to keep bad people out, they are hypocrites to suggest it is not okay for Trump to protect Americans.Fact is, the same ISIS who vowed to import terrorists disguised as refugees doesn’t care about which side of the political aisle a person sits. America experienced an unprecedented number of domestic terrorist attacks committed by Muslim immigrants or children of immigrants during Obama’s tenure.We are a nation governed by the rule of law, but you’d never know it from leaders standing in defiance over Trump’s stance on immigration and sanctuary cities. Sanctuary cities are illegal and in a civil society, those who break the law are punished. Leaders who break federal immigration laws already on the books should be removed from office, fined, and criminally charged. They should be held personally liable for lives lost and havoc wreaked by illegals living within their jurisdictions.Texas Governor Greg Abbott leads the way, promising to pursue legislation to remove sheriffs and mayors breaking immigration laws.Miami-Dade Mayor Carlos Gimenez also denounced Miami-Dade’s previous stance as a sanctuary county on January 27.In my home, my father’s word was law. When Dad said “no” he meant no. Throwing temper tantrums didn’t help. In fact, it made things worse. It’s obvious to me that America has suffered from a significant shortage of alpha male leadership in families, based on the number of people losing their minds over a true leader occupying the White House.Leftists can chuck bricks, throw rocks, and start fires all they want, but Trump will still be president when they wake the next morning.Their actions hurt their cause, because it helps normal people see Democrats don’t really care about anyone but themselves. They claim they are pro-immigrant, but on Inauguration Day in D.C., anti-Trump anarchists set fire to a limousine owned by a Muslim immigrant. The rocks they pelt sent his employee to the hospital. That makes them about as pro-immigrant as they are pro-Christian.As you might expect, a couple of Hillary’s “Deplorables” came to the poor guy’s rescue, raising more than $20,000 to assist him after leftists destroyed his livelihood.But, be of good cheer, there’s a new sheriff in town who likes law and order. Sorry, snowflakes, all those “free spaces” to destroy other people’s stuff are no longer available. That’s why 230 Inauguration Day anarchists were charged with felony rioting and face fines of up to $25,000 and 10 years in prison, which should be time enough to keep them off the streets while Trump cleans up America.All the fit-throwing reminds me this is going to be a long 8 years, but then I smile because I know liberals are thinking the same thing.FacebookTwitterCopy LinkEmailSharelast_img read more

Veteran and former Hoboken resident dies at 75

first_img× HOBOKEN — Thomas Patrick O’Brien died Wednesday Dec. 6 at his home at the age of 75.O’Brien was born on April 19, 1942, in Hoboken, N.J., to Thomas J. and Marion Soldati O’Brien.He was raised in the Hoboken area and attended local schools, graduating from Demarest High School in 1960 and then joined the United United States Marine Corps where he served for four years before joining the New Jersey State Police and retiring as captain after 28 years. After retirement he worked for the Drug Enforcement Administration.O’Brien and his wife Joanne Biel lived in Harvard Idaho and he is survived by his wife of 52 years, Joanne; daughters Shelly (Joe) Michalak and Tara O’Brien; son Tom O’Brien and fiancé Kyla Drumm; grandchildren Sara, Hannah, Dustin, Patrick and Gracie; his brothers, Dennis and Ritchie O’Brien; and sister Colleen DeCandia.Funeral services will be held at 1 p.m. Tuesday at the Princeton Church of the Nazarene, 1008 Gold Hill Road, Princeton, with Pastor Kathy Kramer presiding.In lieu of flowers, the family suggests that donations in Tom’s memory be made to Palouse Care, 1515 W. A St., Moscow, ID 83843; or First Responders Outreach/Gary Sinise Foundation https://www.garysinisefoundation.org/programs/first-responders-outreach.Arrangements have been entrusted to Short’s Funeral Chapel of Moscow and condolences may be left at www.shortsfuneralchapel.com.last_img read more

After 73 years, Wiesenthal’s Auto Service Closes

first_imgDon Wiesenthal watches as grandson Noah jacks up a car. (Photo courtesy Wiesenthal Auto Service)“Glenn has been a lot more involved with the business than I have for a number of years now,” Don said. “He’s good at setting the prices for repairs and handling the paperwork associated with the business. We will apply that knowledge in the future. He knows so much about BMW automobiles that dealers call him when they are having a repair issue they can’t handle.”Don said he will likely concentrate on his hobby: working on his three classic Ford cars: a pair of 1963 Galaxy models and a ’61 Thunderbird. He keeps them purring like kittens and takes them out for car shows on the Boardwalk or for parades in town. He said that he has been organizing his tools and his garage at his Somers Point home since the business closed last week. His wife Jan and the rest of the family will be seeing a lot more of him as he plots his next move. “I don’t want to say we were blindsided, but we didn’t have a whole lot of notice, either,” he said. “I’ve been so focused on getting all of our heavy equipment out of there and into storage and all the other things we had to finish up, the closing really hasn’t hit me yet.”“When they finally knock down the building, that is when I will probably realize it’s over,” he added. “As long as the building is still there it seems like (Wiesenthal’s) is still alive.  That’s where the memories are. We’ll always have those memories. But they won’t live there anymore when there’s a bank on that corner.”The Wiesenthal brothers prepare to remove their sign to close the shop. (Photo courtesy of Wiesenthal Auto Service) Don, left, and Glenn Wiesenthal atop the roof of their repair shop prior to dismantling the sign. (Photo courtesy Kim Wiesenthal) By Tim KellyWhen a business has continuously operated in Ocean City for 73 years and at the same location for the last 51, it’s not a stretch to call that business an institution.In the case of Wiesenthal’s Auto Repair, which closed its doors for the last time on Saturday afternoon, it wasn’t just the end of a local landmark. It was the close of another chapter in Ocean City history.Much of the growth of Ocean City as a tourist destination was built in the post-World War II years when automobile travel exploded nationwide. Most middle-class families from Philadelphia and its suburbs no longer needed a train or bus. They simply piled into the family car and made the hour’s jaunt to the South Jersey Shore.A big part of creating that travel boom was the abundance of gas stations and repair shops along the way as well as here in town. But no more. “We were the last of the Mohicans,” said Don Wiesenthal, 73, co-owner of the repair shop at 860 West Avenue, the northwest corner of 9th Street and West Avenue, with his 66-year-old brother, Glenn.  “People are going to adapt, but what they are going to lose is the convenience,” he said. “There are other places to get gas or to get your car fixed, but they’re a little bit off the beaten track. We were in the corridor.”“There should always be a gas station and a repair shop right here,” he went on. “I’m not saying it should necessarily be us, it could be another owner. What I’m saying is, it’s best for the town to keep a repair shop and a gas station right there.” Moe Wiesenthal founded the business at its original location at 8th and Asbury, in 1946. (Photo courtesy Wiesenthal’s Auto Service Facebook page)These sentiments are not those of a disgruntled former business owner. They are shared by many customers and online reviewers, who gave Wiesenthal’s a 4.5 star (out of five) rating.“Just by talking to the people you can tell it’s a family business,” one reviewer praised. “Friendly staff that does good work at an extremely fair price.”“The job came in $50 under the estimate,” said another. “Excellent service and very accommodating!”These are not cherry-picked good reviews, but rather the norm, and an affirmation of Wiesenthal’s original mission when it was founded by Don and Glenn’s father, Moe.“We always operated on the assumption that if you were straight with people and good with them, they would return and give you repeat business,” Don said. The gas station that shared the same building with Wiesenthal’s repair shop had been sold and independently operated for a few years. When that gas station and the Sunoco station next door shuttered last fall, it spelled the end of gas stations along 9th Street, the main artery in and out of town.The lone remaining spot to purchase gas on the island now is the Sunoco at 34th Street and West Avenue.  The Wiesenthals had attempted to relocate in Ocean City and also in Somers Point and in a part of Marmora that was convenient to Ocean City customers. Those plans did not work out, and the brothers reluctantly made the decision to retire.“When it became clear we couldn’t keep it going, we tried to wrap up the jobs we were working on and then steer people to other (repair) places in town,” Don Wiesenthal said. Employees, from left, Aaron Molett, and Chris Hartman and the Wiesenthal brothers on their final day of business. (Photo courtesy Kim Wiesenthal)Their employee mechanics Chris Hartman and Aaron Molett landed on their feet and will continue to work in Ocean City at Millevoi Best Tire’s repair shop at 604 Asbury Avenue. However, the gaping hole at 9th and West will remain long after the building is replaced, reportedly by a branch of Republic Bank.“The thing I remember most is my dad was always there,” said Kim Wiesenthal. “If I had a problem … and by that I don’t mean it had to be a car problem, dad was always there.”She moved away from Ocean City for a time, but when she returned to live here five years ago, the familiar shop picked right up where it had left off in her life, Kim said. “There were a lot of weeks where I would be at the shop with my son (10-year-old Noah) just about every day,” she said. “Noah learned how to change lights on a car, how to take off a tire. We spent a lot of time there.”The Wiesenthals lost their lease of the building in November and scrambled to find a way to keep it open. “We wanted to figure out a way, especially for all the elderly people who can’t always take care of routine maintenance or change a tire or just get some free air for their tires,” Don Wiesenthal said. “There’s so much construction going on in Ocean City and I’ve always said construction and flat tires go hand in hand.”“I worry about all the older folks, and guess what? Now I am one of those retirees,” he continued.He said he will steer his former customers to Best Tire and to Island Auto Repair at 713 Haven Ave.As for the future, Glenn Wiesenthal will focus on his involvement with the BMW Racing team and test track driving, his brother said. Glenn and his wife Joyce have a son, Grant, 35.last_img read more

Aberna revamps La Pavoni range

first_imgEquipment supplier Aberna (Ash Vale, Surrey) says it has improved its range of La Pavoni coffee machines. The Hotel range, based on Aberna’s Bar machines, are more compact, it says. Available in black or red, the Hotel range produces high volumes of coffee from a limited space.Aberna has also updated its Pub range to include a stainless steel back plate and front, available with either red or black panels. The Pub machines, for smaller sites, make cappuccinos and espressos, as well as tea. There is a choice of either one- or two-group machines, depending on throughput.last_img

Bakery suet supplier rivals Premier

first_imgA new suet manufacturer has set up in direct competition to industry giant Premier Foods.Prima Foods UK is producing up to 30 tonnes of suet a week for bakers, food manufacturers and wholesalers. It supplies multiples such as Tesco, Morrisons and The Co-operative Group as well as small independent retailers. “We opened last year, but have been up and running since January,” said MD Peter Rice. “We aim to offer an alternative to Premier’s Atora product – we’re a small business that looks after people at the right price.”Rice said it had the capacity to produce 50 tonnes of suet a week – shredded fat coated with flour. Products include a non-hydrogenated vegetable suet with sunflower and wheat flour, a non-hydrogenated vegetable suet with rape seed and wheat four, beef suet and suet blends, including chickpea flour. New products include mixes such as herb and sweet dumplings.Bakers are buying suet to make dumplings, suet puddings and desserts, said Rice. “With the recession still ongoing, people are going back to more home cooking and traditional, comfort food that’s filling, and suet fits the bill perfectly.”He added: “We are price-competitive with Premier and can offer small amounts to craft bakers.”last_img read more

Bakers make Profit Track 100 listing

first_imgA number of bakery and food manufacturing firms have been included in The Sunday Times’ Profit Track 100 list.The league table has positioned Noble Foods, based in Tring, Hertfordshire, as part of its top 100 British private firms with the fastest-growing profits, based on the last three years of available accounts.The egg product manufacturer has reported profit growth of 66% per annum, with its latest profits totalling £27m and a base profit of £5.9m. Fullers Foods, the Leeds-based frozen food specialist, came 71st in the list, with £7.8m worth of profits and a 52% annual increase in profit growth.Midlands-based bakery chain Patisserie Valerie has come in at 79 and the second time the company has been featured on the list. It reported a 48% rise in profit growth per annum and its latest profits accumulated to £5.6m.Paul May, chief executive officer, Patisserie Valerie, said: “This is a fantastic period of growth for us as a company, and for this continued success to be recognised on a national level is another great achievement for us.“I believe our individual success is down to organic openings and acquisitions for the national roll-out of the Patisserie Valerie brand across the UK. To be the only company of our kind on the list is a true testament to the hard work that goes in across the board to make the chain a success.”Businesses included on The Sunday Times list typically employ between 100 and 1,000 employees, have an average three-year profit growth ranging from 40% to 210% per annum, and profits between £3m and £35m.last_img read more

PREMIERE: Magic Beans Share Funky New Track From Cervantes-Inspired Album

first_imgMagic Beans have steadily built upon their national notoriety in a very short period of time with a passion for music that is as infectious as their songs. Hailing from Denver, their development has been aided by the warm hearth of the Colorado music scene, quickly setting themselves apart from the pack as one of the state’s premier acts. Magic Beans’ new album, Casino Cabaret–due out this Friday, March 16th–is titled in homage to the vintage sign that hangs above Cervantes Masterpiece Ballroom located in the Five Points area of Denver. The venue has served as the heartbeat of the Denver music scene for decades under different monikers. Its a place where the legends of jazz, soul, and funk found a common stage, and inspired the Magic Beans to craft an album capturing the different styles and genres that can be heard any given night down in Five Points. With Casino Cabaret, the band looks to bring the heart, the vibes, and the feelings of those Denver nights coast to coast.Holing up in the foothills of Colorado at Scanhope Sound studios, Magic Beans–comprised of Scott Hachey, Casey Russell, Chris Duffy and Cody Wales–looked to build upon their past studio experiences and hone in on the new sound they’ve been building since their last release. Taking the time to make these songs come to life, adding some brass to their already full sound, and dialing in the tones on analog equipment, they found ways to add layers to the songs in a way not possible to achieve live.Live For Live Music is thrilled to share the exclusive premiere for “Give Me Somethin Real” ahead of the album’s release. As keyboardist Casey Russell describes it, “‘Give Me Something Real’ is a love song that intertwines the feelings of romance with the love of music –two of the best things in world! It’s a feel-good tune with a nice groove that you can shake your booty to”. Damn straight. Listen to the funky track below:With appearances in 2018 at some of the scenes marquee festivals, a stacked touring schedule and hosting their own Beanstalk Music Festival every June in Colorado, Magic Beans are poised to bust out across the scene and make waves for many years to come.MAGIC BEANS – CASINO CABARET TOUR3/16 – Cervantes Masterpiece Ballroom – Denver, CO3/17 – Aggie Theatre – Fort Collins, CO3/30 – Animas Theatre – Durango, CO3/31 – Liberty Bar – Telluride, CO4/06 – 8×10 – Baltimore, MD4/07 – Iron Works – Buffalo, NY4/11 – Brooklyn Bowl – Brooklyn, NY w/ Ghost Light4/12 – The Hollow – Albany, NY4/13 – Nectar’s – Burlington, VT4/14 – The Acoustic – Bridgeport, CT4/15 – Gypsy Sally’s – Washington, DC4/20 – The Fillmore – Philadelphia, PA w/ The Disco Biscuits5/17-5/18 – DomeFest – Bedford, PA5/19 – Kings Rook – Erie, PA5/20 – The Magic Bag – Ferndale, MI6/28-6/30 – Beanstalk Music & Arts Festival – Bond, CO7/12-7/15 – Camp Bisco – Scranton, PA7/19-7/22 – Peach Music Festival – Scranton, PAView All Tour DatesIn addition to the Magic Beans schedule, keyboardist Casey Russel recently announced an all-star tribute to Prince in New Orleans on Sunday, May 6th, featuring vocalist Corey Frye of The Main Squeeze, guitarist Ryan Jalbert and vocalist Lyle Divinsky of The Motet, bassist Dwayne “MonoNeon” Thomas Jr. of Prince’s band, drummer Robert “Sput” Searight, saxophonist Chris Bullock, and trumpeter Mike “Maz” Maher from Snarky Puppy, vocalists Sammi Garett and Shira Elias of Turkuaz, keyboardist Steve Swatkins of Allen Stone’s band, percussionist Jeff Franca of Thievery Corporation, and Megan Letts of Mama Magnolia will all take part in this special tribute set. Casey will act as musical director, steering the ship as this 13-piece super group delivers the best of Prince’s extensive catalog. For more information on the “Purple Party”, head here.last_img read more

4 tricks for fall road-tripping on a budget

first_img 85SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblr,Wendy Moody Wendy Moody is a Senior Editor with CUInsight.com. Wendy works with the editorial team to help edit the content including current news, press releases, jobs and events. She keeps … Web: www.cuinsight.com Details Fall is the perfect time for a road trip. The leaves are changing and there’s so much beautiful scenery to take in. Before you hit the road, take a hard look at your budget and plan accordingly. Here are 4 tips to consider for your autumn road trip that can save you big before the pricey holiday season.Get a tune upBefore you take off on your road trip be sure your vehicle is in tip-top shape. Getting a legitimate tune up and inflating your tires to the proper pressure will ensure you’re riding in a safe car. It will also help prevent you from making costly repairs to your vehicle down the road.Stock upWe all know eating out can cost a ton, but so can simple snacks purchased at convenience stores. If you pack a cooler with your favorite food and drinks, you can skip those frequent stops at fast food chains and gas station markets. Then, you can save up for more enjoyable meals when you reach your destination.Go mobile and save on gasOver 70 million people have downloaded the GasBuddy app, which helps travelers locate gas stations near them, and most importantly the ones carrying the cheapest gas. When mapping out your trip, plan in advance to fuel up at these more economical gas stops. This will help you budget ahead of time and give you a better idea of how much extra spending money will be left over.Book outside the boxCan you think of the last time you spent less than $100 on a hotel room? The key to saving on accommodations is to think outside the box and step out of your comfort zone. Couchsurfing.com connects travelers with local “hosts” and gives them the opportunity to stay for free (and safely) at the home of someone in the area.last_img read more

NAFCU Board and staff, at work in Washington, meet with agency leaders

first_imgNAFCU – the industry’s Washington Watchdog – has been recognized with award-winning advocacy, and while NAFCU lobbyists were having non-stop meetings on Capitol Hill, the association’s Board of Directors further showcased this prowess while in Washington this week holding high-profile meetings with leaders of the Bureau of Consumer Financial Protection and Federal Reserve.In addition to handling necessary board business, the NAFCU Board – met Monday and Tuesday with bureau Acting Director Mick Mulvaney and Fed Vice Chairman of Supervision Randal Quarles to share credit unions’ perspective on various initiatives being pursued by the agencies.Bureau of Consumer Financial ProtectionDuring Monday’s meeting with Mulvaney, the NAFCU Board shared credit unions’ priorities and regulatory concerns heading into the new year. continue reading » ShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblrlast_img read more